rdf:type |
|
lifeskim:mentions |
umls-concept:C0010760,
umls-concept:C0012929,
umls-concept:C0017337,
umls-concept:C0027293,
umls-concept:C0035711,
umls-concept:C0040935,
umls-concept:C0162802,
umls-concept:C0439855,
umls-concept:C1537993,
umls-concept:C1537994,
umls-concept:C1537998,
umls-concept:C1711351
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pubmed:issue |
3
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pubmed:dateCreated |
1992-10-20
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pubmed:databankReference |
|
pubmed:abstractText |
In this paper, we present the nucleotide sequence of a 5248 bp-long region of the mitochondrial (mt) genome of the dermatophyte Trichophyton rubrum. This region which represents about 1/4 of the total mt genome of this species reveals a compact organization of genes including: the glutaminyl tRNA, the methionyl tRNA, the cytochrome oxidase subunit I gene, the arginyl tRNA, the mitochondrial version of the ATPase subunit 9 gene, the cytochrome oxidase subunit II gene and a part of the NADH dehydrogenase ND4L and ND5 gene "complex". The main features of the part of mt DNA sequenced is the non-interrupted COXI gene and the presence in the mitochondrial version of the ATPase 9 gene of a small group IA intron. The extensive amino-acid sequence similarity with the equivalent gene in Aspergillus nidulans and Neuropora crassa indicates that this gene codes for a dicyclohexylcarbodiimide binding protein. The conserved arrangement of this portion of the mt genome and the presence of tRNAs between the protein-coding genes are compatible with a large polycistronic transcript processed by the excision of tRNAs, or similar secondary structures, as proposed for other fungal or mammalian mt DNAS.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphatases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Mitochondrial,
http://linkedlifedata.com/resource/pubmed/chemical/Electron Transport Complex IV,
http://linkedlifedata.com/resource/pubmed/chemical/NADH Dehydrogenase,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Transfer, Amino Acyl,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Transfer, Met,
http://linkedlifedata.com/resource/pubmed/chemical/tRNA, arginine-,
http://linkedlifedata.com/resource/pubmed/chemical/tRNA, glutamine-
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0172-8083
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:geneSymbol |
ND4L,
ND5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1326416-Adenosine Triphosphatases,
pubmed-meshheading:1326416-Amino Acid Sequence,
pubmed-meshheading:1326416-Base Sequence,
pubmed-meshheading:1326416-DNA, Fungal,
pubmed-meshheading:1326416-DNA, Mitochondrial,
pubmed-meshheading:1326416-Electron Transport Complex IV,
pubmed-meshheading:1326416-Genes, Fungal,
pubmed-meshheading:1326416-Introns,
pubmed-meshheading:1326416-Molecular Sequence Data,
pubmed-meshheading:1326416-NADH Dehydrogenase,
pubmed-meshheading:1326416-Nucleic Acid Conformation,
pubmed-meshheading:1326416-RNA, Fungal,
pubmed-meshheading:1326416-RNA, Transfer, Amino Acyl,
pubmed-meshheading:1326416-RNA, Transfer, Met,
pubmed-meshheading:1326416-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1326416-Trichophyton
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pubmed:year |
1992
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pubmed:articleTitle |
Mitochondrial DNA sequence analysis of the cytochrome oxidase subunit I and II genes, the ATPase9 gene, the NADH dehydrogenase ND4L and ND5 gene complex, and the glutaminyl, methionyl and arginyl tRNA genes from Trichophyton rubrum.
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pubmed:affiliation |
Unité de Mycologie, Institut Pasteur, Paris, France.
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pubmed:publicationType |
Journal Article
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