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| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C0679729 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C0242210 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C0439659 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C0013879 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:1324937 | lifeskim:mentions | umls-concept:C2369738 | lld:lifeskim |
| pubmed-article:1324937 | pubmed:issue | 24 | lld:pubmed |
| pubmed-article:1324937 | pubmed:dateCreated | 1992-9-25 | lld:pubmed |
| pubmed-article:1324937 | pubmed:abstractText | The origin binding protein (OBP) of herpes simplex virus type 1 is required to activate a viral origin of replication in vivo. We have used intact OBP as well as a truncated form of the protein expressed in Escherichia coli to investigate the protein-protein interactions, as well as the protein-DNA interactions involved in the formation of a nucleoprotein complex at a viral origin of replication (oriS) in vitro. The salient findings demonstrate that the N-terminal part of OBP is required for the cooperative binding of OBP to three sites (boxes I, II, and III) within oriS. A detailed model for the interaction of OBP with the viral origins of replication oriS and oriL is presented. | lld:pubmed |
| pubmed-article:1324937 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1324937 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1324937 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1324937 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1324937 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1324937 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:1324937 | pubmed:author | pubmed-author:TJAYJ KJK | lld:pubmed |
| pubmed-article:1324937 | pubmed:author | pubmed-author:EliasPP | lld:pubmed |
| pubmed-article:1324937 | pubmed:author | pubmed-author:GustafssonC... | lld:pubmed |
| pubmed-article:1324937 | pubmed:author | pubmed-author:HammarstenOO | lld:pubmed |
| pubmed-article:1324937 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1324937 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:1324937 | pubmed:volume | 267 | lld:pubmed |
| pubmed-article:1324937 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1324937 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1324937 | pubmed:pagination | 17424-9 | lld:pubmed |
| pubmed-article:1324937 | pubmed:dateRevised | 2007-10-11 | lld:pubmed |
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| pubmed-article:1324937 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1324937 | pubmed:articleTitle | Structural elements required for the cooperative binding of the herpes simplex virus origin binding protein to oriS reside in the N-terminal part of the protein. | lld:pubmed |
| pubmed-article:1324937 | pubmed:affiliation | Department of Medical Biochemistry, University of Göteborg, Sweden. | lld:pubmed |
| pubmed-article:1324937 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1324937 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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