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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1992-8-20
|
| pubmed:abstractText |
The infantile hepatitis syndrome is defined as a liver disease which occurs during the infantile period with the clinical manifestation of jaundice, hepatomegaly and hepatic dysfunction. The cause of disease is complex and the treatment is difficult. From March 1987 to June 1988, 55 patients (treatment group) were treated with injection of yin zhi huang, and 15 cases (control group) with injection of Inosine, vitamin C and glucose. The course of treatment lasted 15 days. At the beginning and the end of the treatment, serum bilirubin level, sALT level, duodenal juice bilirubin level, liver size and T cell subsets in peripheral blood had been detected separately. The results showed that among the treatment group, serum bilirubin level was significantly lower at the end of the treatment than that of the control group. The sALT, and hepatomegaly were also reduced or lessened, while the duodenal juice bilirubin level was increased. But there was no difference in T cell subsets between the two groups.
|
| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Age Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Asia,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/CHINA,
http://linkedlifedata.com/resource/pubmed/keyword/Case Control Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Eastern Asia,
http://linkedlifedata.com/resource/pubmed/keyword/Hepatic Effects,
http://linkedlifedata.com/resource/pubmed/keyword/IMMUNITY,
http://linkedlifedata.com/resource/pubmed/keyword/Immunological Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Infant,
http://linkedlifedata.com/resource/pubmed/keyword/Liver Dysfunction,
http://linkedlifedata.com/resource/pubmed/keyword/Organization And Administration,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Population,
http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics,
http://linkedlifedata.com/resource/pubmed/keyword/Pre-post Tests,
http://linkedlifedata.com/resource/pubmed/keyword/Program Evaluation,
http://linkedlifedata.com/resource/pubmed/keyword/Programs,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Youth
|
| pubmed:language |
chi
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1003-5370
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
26-7, 5-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:otherAbstract |
PIP: Infantile hepatitis syndrome is a liver disease which occurs during the infantile period with the clinical manifestation of jaundice, haptomegaly, and liver dysfunction. The cause of the disease is complex, and, currently, no medicine can provide satisfactory treatment. Yinzhihuang injectable has been found to be effective in treating infantile jaundice, and acute and chronic hepatitis and, therefore, its effectiveness in treating infantile hepatitis syndrome was tested. From March 1987 to June 1988, 55 infants with hepatitis syndrome were treated with Yinzhihuang injection for 1 or 2 15-day cycles, and 15 infants randomly chosen to be the controls received injections of Inosine, vitamin C, and glucose. Serum bilirubin level, liver SALT levels, duodenal juice bilirubin level, liver size, and T cell subsets in peripheral blood were tested both before and after the treatment. The results showed that the treatment group experiences a significant decline of serum bilirubin level and a reduction in liver size after the treatment, while the differences for the control group were not significant. The duodenal juice bilirubin level of the treatment group increased, but the difference was not statistically significant. Both the treatment and the control group experienced a reduction of CD+4 to normal level, but CD+8 for both groups was still high, which indicated that Yinzhihuang can not regulate cell immunological functioning in a short term. Nevertheless, its longterm impact on immunological functions needs to be further explored.
|
| pubmed:meshHeading |
pubmed-meshheading:1320965-CD4-CD8 Ratio,
pubmed-meshheading:1320965-Cytomegalovirus Infections,
pubmed-meshheading:1320965-Drugs, Chinese Herbal,
pubmed-meshheading:1320965-Female,
pubmed-meshheading:1320965-Hepatitis,
pubmed-meshheading:1320965-Hepatomegaly,
pubmed-meshheading:1320965-Humans,
pubmed-meshheading:1320965-Infant,
pubmed-meshheading:1320965-Infant, Newborn,
pubmed-meshheading:1320965-Injections,
pubmed-meshheading:1320965-Jaundice,
pubmed-meshheading:1320965-Male,
pubmed-meshheading:1320965-Syndrome,
pubmed-meshheading:1320965-T-Lymphocyte Subsets
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
[Treatment of infantile hepatitis syndrome with injection of yin zhi huang].
|
| pubmed:affiliation |
Dept. of Pediatrics, Tongji Hospital, Tongji Medical University, Wuhan.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|