rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
1992-7-14
|
pubmed:abstractText |
Growth hormone (GH), blood pressure, and pulse rate responses to clonidine (100 micrograms IV) were studied three times during the first week of alcohol withdrawal in 19 alcohol-dependent patients. Fifteen healthy men were used as controls. The results suggest reduced sensitivity of the alpha-2-adrenoceptors involved in GH secretion for at least 1 week after the end of alcohol intake. In contrast, very short-lasting subsensitivity was found in the alpha-2-adrenoceptors regulating blood pressure.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0006-3223
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
712-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1318083-Adult,
pubmed-meshheading:1318083-Alcohol Withdrawal Delirium,
pubmed-meshheading:1318083-Blood Pressure,
pubmed-meshheading:1318083-Chlormethiazole,
pubmed-meshheading:1318083-Chlorprothixene,
pubmed-meshheading:1318083-Clonidine,
pubmed-meshheading:1318083-Dose-Response Relationship, Drug,
pubmed-meshheading:1318083-Drug Therapy, Combination,
pubmed-meshheading:1318083-Female,
pubmed-meshheading:1318083-Growth Hormone,
pubmed-meshheading:1318083-Humans,
pubmed-meshheading:1318083-Male,
pubmed-meshheading:1318083-Middle Aged,
pubmed-meshheading:1318083-Norepinephrine,
pubmed-meshheading:1318083-Oxazepam,
pubmed-meshheading:1318083-Receptors, Adrenergic
|
pubmed:year |
1992
|
pubmed:articleTitle |
Alpha-2-adrenoceptor sensitivity in early alcohol withdrawal.
|
pubmed:affiliation |
Department of Psychiatry and Neurochemistry, University of Göteborg, Sweden.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|