rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
3
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pubmed:dateCreated |
1992-6-29
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pubmed:abstractText |
The in-vitro activity of four peptide antibiotics against 43 penicillin-resistant Streptococcus pneumoniae isolated from cerebrospinal fluid (CSF) was evaluated. The activity of SKF104662 was slightly greater to that of vancomycin, teicoplanin and daptomycin (MICs for 90% of the isolates tested 0.06, 0.25, 0.12 and 0.25 mg/L, respectively) and superior to the other 15 drugs tested. The serotype of these penicillin-resistant strains was also determined. The strains that belonged to the predominant serotype 9 were resistant only to penicillin. All six erythromycin- and clindamycin-resistant strains belonged to serotype 6 and three of them were also resistant to chloramphenicol and tetracycline (plus penicillin).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Infective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Daptomycin,
http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Fluoroquinolones,
http://linkedlifedata.com/resource/pubmed/chemical/Glycopeptides,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Quinolones,
http://linkedlifedata.com/resource/pubmed/chemical/SK&F 104662,
http://linkedlifedata.com/resource/pubmed/chemical/Teicoplanin,
http://linkedlifedata.com/resource/pubmed/chemical/Vancomycin,
http://linkedlifedata.com/resource/pubmed/chemical/temafloxacin
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0305-7453
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
299-302
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1317370-Anti-Bacterial Agents,
pubmed-meshheading:1317370-Anti-Infective Agents,
pubmed-meshheading:1317370-Cerebrospinal Fluid,
pubmed-meshheading:1317370-Daptomycin,
pubmed-meshheading:1317370-Erythromycin,
pubmed-meshheading:1317370-Fluoroquinolones,
pubmed-meshheading:1317370-Glycopeptides,
pubmed-meshheading:1317370-Humans,
pubmed-meshheading:1317370-Microbial Sensitivity Tests,
pubmed-meshheading:1317370-Penicillin Resistance,
pubmed-meshheading:1317370-Peptides,
pubmed-meshheading:1317370-Quinolones,
pubmed-meshheading:1317370-Serotyping,
pubmed-meshheading:1317370-Streptococcus pneumoniae,
pubmed-meshheading:1317370-Teicoplanin,
pubmed-meshheading:1317370-Vancomycin
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pubmed:year |
1992
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pubmed:articleTitle |
Comparative in-vitro activity of four peptide antibiotics against penicillin-resistant Streptococcus pneumoniae isolated from cerebrospinal fluid (CSF).
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pubmed:affiliation |
Servicio de Bacteriología, Centro Nacional de Microbiología, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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