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| pubmed-article:1316171 | lifeskim:mentions | umls-concept:C0596901 | lld:lifeskim |
| pubmed-article:1316171 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
| pubmed-article:1316171 | lifeskim:mentions | umls-concept:C0002812 | lld:lifeskim |
| pubmed-article:1316171 | lifeskim:mentions | umls-concept:C1704242 | lld:lifeskim |
| pubmed-article:1316171 | lifeskim:mentions | umls-concept:C0001473 | lld:lifeskim |
| pubmed-article:1316171 | lifeskim:mentions | umls-concept:C0006556 | lld:lifeskim |
| pubmed-article:1316171 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1316171 | pubmed:dateCreated | 1992-6-12 | lld:pubmed |
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| pubmed-article:1316171 | pubmed:abstractText | We have cloned and sequenced a cDNA for the rabbit gastric proton-potassium pump (H+/K(+)-ATPase) alpha-subunit. The deduced peptide contains 1035 amino acids (Mr 114,201) and shows 97% sequence identity with the respective rat and hog proteins. A monoclonal antibody 146-14 has been shown previously to react with the extracytoplasmic side of the catalytic H+/K(+)-ATPase subunit and here we show that the epitope is in the region between amino acids 855 and 902 (the numbering of the H+/K(+)-ATPase catalytic subunit throughout the paper refers to the rabbit sequence). The localization of this epitope in conjunction with previously observed trypsin cleavage sites in the C-terminal one third of the enzyme and the hydrophobicity plot of the deduced peptide sequence are evidence for a structural model for the alpha-subunit of the H+/K(+)-ATPase which contains at least ten membrane spanning segments, similar to that deduced for the Ca(2+)-ATPase of sarcoplasmic reticulum. | lld:pubmed |
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| pubmed-article:1316171 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1316171 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1316171 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1316171 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1316171 | pubmed:month | May | lld:pubmed |
| pubmed-article:1316171 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:1316171 | pubmed:author | pubmed-author:KobayashiYY | lld:pubmed |
| pubmed-article:1316171 | pubmed:author | pubmed-author:SachsGG | lld:pubmed |
| pubmed-article:1316171 | pubmed:author | pubmed-author:ReubenM AMA | lld:pubmed |
| pubmed-article:1316171 | pubmed:author | pubmed-author:MercierFF | lld:pubmed |
| pubmed-article:1316171 | pubmed:author | pubmed-author:MunsonK BKB | lld:pubmed |
| pubmed-article:1316171 | pubmed:author | pubmed-author:BambergKK | lld:pubmed |
| pubmed-article:1316171 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1316171 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:1316171 | pubmed:volume | 1131 | lld:pubmed |
| pubmed-article:1316171 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1316171 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1316171 | pubmed:pagination | 69-77 | lld:pubmed |
| pubmed-article:1316171 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:1316171 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1316171 | pubmed:articleTitle | cDNA cloning and membrane topology of the rabbit gastric H+/K(+)-ATPase alpha-subunit. | lld:pubmed |
| pubmed-article:1316171 | pubmed:affiliation | Department of Physiology, School of Medicine, UCLA. | lld:pubmed |
| pubmed-article:1316171 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1316171 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1316171 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:1316171 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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