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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-6-4
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pubmed:abstractText |
Subgingival plaque samples were collected from individuals with advanced periodontitis before and 3 to 11 weeks after scaling and root planing periodontal treatment. The plaque levels of Treponema denticola and Porphyromonas gingivalis antigens were measured before and after treatment by a quantitative immunoassay procedure using monoclonal antibodies specific for these oral bacteria. A decrease in mean levels of T. denticola (P less than .05) and P. gingivalis antigens (P less than .09) were observed following periodontal therapy. Improved health, as measured by a decrease in probing depth, was associated with a decrease in T. denticola antigen (P less than .05). These results suggest that the T. denticola levels of successfully treated sites decreased, while non-responding sites had levels of this microbial marker which were equal to or greater than the pre-treatment levels. These results provide additional evidence that T. denticola is associated with human adult severe periodontal disease, and can serve as a prognostic marker for disease recurrence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-3492
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
270-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1315388-Adult,
pubmed-meshheading:1315388-Aged,
pubmed-meshheading:1315388-Alveolar Bone Loss,
pubmed-meshheading:1315388-Biological Markers,
pubmed-meshheading:1315388-Colony Count, Microbial,
pubmed-meshheading:1315388-Dental Plaque,
pubmed-meshheading:1315388-Dental Scaling,
pubmed-meshheading:1315388-Female,
pubmed-meshheading:1315388-Gingival Hemorrhage,
pubmed-meshheading:1315388-Humans,
pubmed-meshheading:1315388-Male,
pubmed-meshheading:1315388-Middle Aged,
pubmed-meshheading:1315388-Periodontal Pocket,
pubmed-meshheading:1315388-Periodontitis,
pubmed-meshheading:1315388-Porphyromonas gingivalis,
pubmed-meshheading:1315388-Prognosis,
pubmed-meshheading:1315388-Root Planing,
pubmed-meshheading:1315388-Treponema
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pubmed:year |
1992
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pubmed:articleTitle |
Treponema denticola and Porphyromonas gingivalis as prognostic markers following periodontal treatment.
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pubmed:affiliation |
Naval Dental Research Institute, Great Lakes, IL.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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