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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-5-21
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pubmed:abstractText |
Twenty unselected pituitary adenomas have been examined for proliferative indices (PIs), and anterior pituitary hormone expression. All but two of the tumours were non-functional with proliferative indices from less than 0.1 to 0.5%. Two tumours were null cell adenomas with PIs less than 0.1 and 0.2%. The PIs of the three recurrent tumours was less than 1.0%. Gonadotrophin and TSH immunoreactivity was heterogenous and was found in 12/20 (60%) of the tumours. There was no significant relationship between PI, hormone expression or any other measured parameter. The biological behaviour of pituitary adenomas with a PI of less than 0.1% is uncertain, but those with a PI of greater than 0.1% are more likely to recur although longer follow-up is needed to confirm this.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0268-8697
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1314060-Adenoma,
pubmed-meshheading:1314060-Adrenocorticotropic Hormone,
pubmed-meshheading:1314060-Adult,
pubmed-meshheading:1314060-Aged,
pubmed-meshheading:1314060-Bromodeoxyuridine,
pubmed-meshheading:1314060-Cell Division,
pubmed-meshheading:1314060-Female,
pubmed-meshheading:1314060-Humans,
pubmed-meshheading:1314060-Immunohistochemistry,
pubmed-meshheading:1314060-Male,
pubmed-meshheading:1314060-Middle Aged,
pubmed-meshheading:1314060-Neoplasm Invasiveness,
pubmed-meshheading:1314060-Neoplasm Recurrence, Local,
pubmed-meshheading:1314060-Pituitary Neoplasms,
pubmed-meshheading:1314060-Prolactin,
pubmed-meshheading:1314060-Risk Factors
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pubmed:year |
1992
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pubmed:articleTitle |
Pituitary adenoma proliferative indices and risk of recurrence.
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pubmed:affiliation |
Department of Neurosurgery, Midland Centre for Neurosurgery and Neurology.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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