Source:http://linkedlifedata.com/resource/pubmed/id/13130396
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2003-9-17
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pubmed:abstractText |
Supplementation of diets with plant extracts such as ginkgo biloba extract (EGb 761) (definition see editorial) for health and prevention of degenerative diseases is popular. However, it is often difficult to analyse the biological activities of plant extracts due to their complex nature and the possible synergistic and/or antagonistic effects of their components. Genome-wide expression monitoring with high-density oligonucleotide arrays provides one way to examine the molecular targets of plant extracts and may prove a useful tool in evaluating their therapeutic claims. Here, we will briefly describe some of our work on the effect of EGb 761 on differential gene expression in relation to its potential anti-carcinogenic, photoprotective and neuromodulatory properties.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0176-3679
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S95-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:13130396-Animals,
pubmed-meshheading:13130396-Cells, Cultured,
pubmed-meshheading:13130396-Cerebral Cortex,
pubmed-meshheading:13130396-Chromatography, High Pressure Liquid,
pubmed-meshheading:13130396-Dose-Response Relationship, Drug,
pubmed-meshheading:13130396-Female,
pubmed-meshheading:13130396-Gene Expression,
pubmed-meshheading:13130396-Ginkgo biloba,
pubmed-meshheading:13130396-Hippocampus,
pubmed-meshheading:13130396-Humans,
pubmed-meshheading:13130396-Keratinocytes,
pubmed-meshheading:13130396-Mice,
pubmed-meshheading:13130396-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:13130396-Plant Extracts,
pubmed-meshheading:13130396-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:13130396-Time Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Effect of Ginkgo biloba (EGb 761) on differential gene expression.
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pubmed:affiliation |
Hugh Sinclair Human Nutrition Unit, School of Food Biosciences, University of Reading, PO Box 226, Reading RG6 6AP, UK. g.h.rimbach@reading.ac.uk
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pubmed:publicationType |
Journal Article,
Comparative Study
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