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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2-3
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pubmed:dateCreated |
1992-4-13
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pubmed:abstractText |
Erythropoietin (EPO) stimulates proliferation and differentiation of late erythroid precursor cells (CFU-E) and thereby determines the rate of erythropoiesis. Liver is the major erythropoietic site in a fetus. We dealt with developmental changes in CFU-E and EPO receptor (EPO-R) of fetal mouse liver. The affinity of the EPO-R to EPO was unchanged during fetal development. The population size of CFU-E, the number of EPO-R per liver cell, and EPO-R mRNA decreased as gestation proceeded, in a pattern indicating that the expression of EPO-R on erythroid precursor cells in fetal mouse liver is governed mostly by the process of mRNA production.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
298
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
169-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1312022-Animals,
pubmed-meshheading:1312022-Blotting, Northern,
pubmed-meshheading:1312022-Cells, Cultured,
pubmed-meshheading:1312022-Erythropoietin,
pubmed-meshheading:1312022-Liver,
pubmed-meshheading:1312022-Mice,
pubmed-meshheading:1312022-RNA, Messenger,
pubmed-meshheading:1312022-Receptors, Cell Surface,
pubmed-meshheading:1312022-Receptors, Erythropoietin,
pubmed-meshheading:1312022-Recombinant Proteins
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pubmed:year |
1992
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pubmed:articleTitle |
Developmental changes in erythropoietin receptor expression of fetal mouse liver.
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pubmed:affiliation |
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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