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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-2-26
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pubmed:abstractText |
A theoretical model has been elaborated in order to describe the kinetics of Ca2+ release induced by inositol 1,4,5-trisphosphate (IP3). The model is based on the existence of a key molecule that controls the interconversion of open and closed forms of the Ca2+ channel. The model can quantitatively explain the previously obtained experimental observations that showed that a continuous IP3 stimulus leads to a biphasic Ca2+ release and that successive IP3 additions provoke repetitive bursts of Ca2+ release. Other published interpretations of these observations are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
0026-895X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
110-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1310136-Calcium,
pubmed-meshheading:1310136-Calcium Channels,
pubmed-meshheading:1310136-Inositol 1,4,5-Trisphosphate,
pubmed-meshheading:1310136-Kinetics,
pubmed-meshheading:1310136-Mathematical Computing,
pubmed-meshheading:1310136-Models, Biological,
pubmed-meshheading:1310136-Quantum Theory
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pubmed:year |
1992
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pubmed:articleTitle |
Dynamic control of inositol 1,4,5-trisphosphate-induced Ca2+ release: a theoretical explanation for the quantal release of Ca2+.
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pubmed:affiliation |
Institut de Recherche Interdisciplinaire, Université Libre de Bruxelles, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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