Linked Life Data

1308603

Source:http://linkedlifedata.com/resource/pubmed/id/1308603

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-10-4
pubmed:abstractText
Significant increase of liver succinic dehydrogenase (SHD) activity was produced by carrageenin-induced edema in rats. Pretreatment with human placental extract "Placentrex" inhibited the increased liver SHD activity in a dose-dependent manner. "Placentrex" was found to have no effect on the liver SHD activity in normal rats. Furthermore, heat-induced erythrocyte lysis was inhibited to a substantial extent by "Placentrex" and was found to be almost dose-responsive. However, adenosine diphosphate (ADP)-induced platelet aggregation and trypsin activity were not changed in vitro by the "Placentrex". No alkaline phosphatase activity was found in this preparation. All these studies indicate that the membrane stabilization and depletion of adenosine triphosphate (ATP) synthesis may be the basis of anti-inflammatory effect of this drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-291X
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
361-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Anti-inflammatory effect of human placental extract: a biochemical mechanistic approach.
pubmed:publicationType
Journal Article, In Vitro