Linked Life Data

1308178

Source:http://linkedlifedata.com/resource/pubmed/id/1308178

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-9-24
pubmed:abstractText
Mossy cells in the human dentate gyrus of adults and children of different ages were impregnated using the rapid-Golgi method. In every case the cause of death was verified by autopsy and the brains were used when neither the history of the patient nor autopsy revealed brain-related disease. Mossy cells in the human share common light microscopic features with the same cell type in rats and monkeys. Their most characteristic feature is the extremely large and complex excrescences on their proximal dendrites. Distal dendrites display pedunculate spines. Mossy cells have a few somal spines. The axon of mossy cells originates from the cell body and gives rise to several collaterals in the hilar region. The axons could be followed for several hundred microns, but in only one case did an axon collateral enter the granule cell layer of the adult dentate gyrus. In the newborn child, mossy cells display immature somal and dendritic features. The soma frequently bear spines. The dendrites are varicose and terminate in presumed growth cones. Both proximal and distal portions of the dendrites bear a few pedunculate spines and long-irregular filopodia. A few small excrescences are present on the proximal dendrites. The first large, complex excrescences on the proximal dendrites of mossy cells appeared in the 7-month-old child. Both somata and dendrites display adult-like characteristics in mossy cells from a 5-year-old child. However, not all mossy cells are alike and some dendrites still display long filopodia. The axons of immature mossy cells were similar to adults. The present results indicate that connections between granule cells and hilar mossy cells of the human dentate gyrus develop through an extended postnatal period of time that may last until the fifth year.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1050-9631
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Postnatal development of mossy cells in the human dentate gyrus: a light microscopic Golgi study.
pubmed:affiliation
Department of Physiology, University Medical School Pécs, Hungary.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't