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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1993-7-13
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pubmed:abstractText |
A trial of Sulbactam/Ampicillin in treatment of typhoid fever was carried out while in-vitro sensitivity of the drug was compared with chloramphenicol. Sulbactam/Ampicillin was found to be effective in 11 out of 12 patients who received the drug. The 1 patient who failed to respond had intestinal perforation with peritonitis. No side effects were encountered. The in-vitro study showed that 91.7% of the isolates were sensitive to sulbactam/ampicillin compared to 75% sensitivity to chloramphenicol. The difference was however not statistically significant (P < 0.05). It is concluded that sulbactam/ampicillin is effective and safe in the treatment of typhoid infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0189-160X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
11
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
274-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1304791-Adolescent,
pubmed-meshheading:1304791-Adult,
pubmed-meshheading:1304791-Ampicillin,
pubmed-meshheading:1304791-Chloramphenicol,
pubmed-meshheading:1304791-Drug Therapy, Combination,
pubmed-meshheading:1304791-Female,
pubmed-meshheading:1304791-Fever of Unknown Origin,
pubmed-meshheading:1304791-Humans,
pubmed-meshheading:1304791-Male,
pubmed-meshheading:1304791-Microbial Sensitivity Tests,
pubmed-meshheading:1304791-Nigeria,
pubmed-meshheading:1304791-Sulbactam,
pubmed-meshheading:1304791-Typhoid Fever
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pubmed:articleTitle |
Clinical trial of sulbactam/ampicillin in the treatment of typhoid fever, and in-vitro sensitivity of isolates to sulbactam/ampicillin and chloramphenicol.
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pubmed:affiliation |
Department of Medicine, University College Hospital, Ibadan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
|