Linked Life Data

1304616

Source:http://linkedlifedata.com/resource/pubmed/id/1304616

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-7-7
pubmed:abstractText
The serum levels of thyroxine (T4), 3,5,3'-triiodothyronine (T3) and 3,3',5'-triiodothyronine (reverse T3, rT3) were examined from 8 depressed patients who did not maximally benefit from conventional antidepressant therapy. Four of the 8 depressed patients showed significant clinical improvement after thyroid hormone was added to their ongoing antidepressant drugs. The T4 and rT3 levels prior to thyroid hormone supplementation were significantly lower in responders than in nonresponders, although within the normal range. Furthermore, all of the patients who had both their rT3 levels less than 200 pg/ml and T4 levels less than 7 micrograms/dl responded to the thyroid hormone treatment. These data suggest that the lower T4 and rT3 levels can predict the treatment response to the thyroid hormone supplementation in depressed patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0912-2036
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
905-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Comparison of thyroid function between responders and nonresponders to thyroid hormone supplementation in depression.
pubmed:affiliation
Department of Psychiatry, Mie University School of Medicine, Tsu, Japan.
pubmed:publicationType
Journal Article, Comparative Study