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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1993-6-24
|
| pubmed:abstractText |
The profile of the major metabolites of primaquine produced by in vitro liver microsomal metabolism was investigated with silica gel thin-layer and high performance liquid chromatography (HPLC) analysis. The results indicated that the liver microsomal metabolism could simultaneously produce both 5-OH PQ (quinoline ring oxidation product) and CPQ (side-chain oxidative deamination product). However, the quantitative comparative study of microsomal metabolism showed that the production of 5-OH PQ was far much higher than that of CPQ.
|
| pubmed:language |
chi
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1000-7423
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
275-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1992
|
| pubmed:articleTitle |
[In vitro liver microsomal metabolism of antimalarial primaquine].
|
| pubmed:affiliation |
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
English Abstract,
Research Support, Non-U.S. Gov't
|