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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1976-5-10
|
| pubmed:abstractText |
Media conditioned with viable rat and calf spleen lymphocytes were seen to be able to inhibit 3H-thymidine uptake by rat thymocytes and the mitogenic response of human lymphocytes to PHA but not bone marrow cells proliferation. The inhibitor appeared to have a molecular weight greater than 50,000 daltons, as determined by Amicon Diaflo ultrafiltration. Media conditioned with rat granulocytes had a similar tissue specific but species non-specific inhibitory action. Also human leukemic cells appeared able to produce in vitro an inhibitor of cell proliferation when a certain degree of differentiation was present.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0021-2547
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
31
|
| pubmed:volume |
54
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
235-43
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:130146-Animals,
pubmed-meshheading:130146-Bone Marrow Cells,
pubmed-meshheading:130146-Cattle,
pubmed-meshheading:130146-Cells, Cultured,
pubmed-meshheading:130146-Culture Media,
pubmed-meshheading:130146-Growth Inhibitors,
pubmed-meshheading:130146-Humans,
pubmed-meshheading:130146-Leukemia,
pubmed-meshheading:130146-Leukocytes,
pubmed-meshheading:130146-Mitosis,
pubmed-meshheading:130146-Molecular Weight,
pubmed-meshheading:130146-Rats,
pubmed-meshheading:130146-Spleen,
pubmed-meshheading:130146-T-Lymphocytes,
pubmed-meshheading:130146-Ultrafiltration
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
In vitro production of lymphocyte and granulocyte proliferation inhibitors (chalones?) from living cells.
|
| pubmed:publicationType |
Journal Article
|