pubmed-article:1301355 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0005388 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0234421 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0005404 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0015772 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0030883 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C0806140 | lld:lifeskim |
pubmed-article:1301355 | lifeskim:mentions | umls-concept:C1515075 | lld:lifeskim |
pubmed-article:1301355 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:1301355 | pubmed:dateCreated | 1993-6-1 | lld:pubmed |
pubmed-article:1301355 | pubmed:abstractText | Felodipine, a vasoselective dihydropyridine calcium antagonist, has been given i.v. (0.2 mumol/kg) to anaesthetized and conscious male rats. There was no effect of pentobarbital anaesthesia on bile flow over a 6 h observation period. Felodipine increased the 6 h recovery of bile by approximately 25% in the conscious rat but in the anaesthetized rat there was a 20% decrease in bile flow following i.v. felodipine. A positive effect of Na-taurocholate infusion (1 mumol/min/100 g body weight) on bile flow in conscious rats was reinforced by concomitant felodipine dosing. Accumulated 6 h recoveries were 2.32 +/- 0.80 g/100 g body weight (control), 3.09 +/- 0.91 g/100 g body weight (taurocholate) and 5.00 +/- 0.80 g/100 g body weight. (taurocholate plus felodipine). The excretion of felodipine in the bile was significantly reduced during anaesthesia and during infusion of 2% bovine serum albumin (0.01 ml/min/100 g body weight) to conscious rats. | lld:pubmed |
pubmed-article:1301355 | pubmed:language | eng | lld:pubmed |
pubmed-article:1301355 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1301355 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1301355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1301355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1301355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1301355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1301355 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1301355 | pubmed:issn | 0378-7966 | lld:pubmed |
pubmed-article:1301355 | pubmed:author | pubmed-author:RegårdhC GCG | lld:pubmed |
pubmed-article:1301355 | pubmed:author | pubmed-author:SutfinT ATA | lld:pubmed |
pubmed-article:1301355 | pubmed:author | pubmed-author:WangS XSX | lld:pubmed |
pubmed-article:1301355 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1301355 | pubmed:volume | 17 | lld:pubmed |
pubmed-article:1301355 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1301355 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1301355 | pubmed:pagination | 263-8 | lld:pubmed |
pubmed-article:1301355 | pubmed:dateRevised | 2011-2-2 | lld:pubmed |
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pubmed-article:1301355 | pubmed:meshHeading | pubmed-meshheading:1301355-... | lld:pubmed |
pubmed-article:1301355 | pubmed:articleTitle | The effect of felodipine on bile flow in pentobarbital anaesthetized rats and conscious rats receiving bile salt supplementation. | lld:pubmed |
pubmed-article:1301355 | pubmed:affiliation | Astra Hässle AB, Mölndal, Sweden. | lld:pubmed |
pubmed-article:1301355 | pubmed:publicationType | Journal Article | lld:pubmed |