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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1993-5-26
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pubmed:abstractText |
Epididymal (E) and prostatic (P) segments of the rat vas deferens were incubated with tritium-labeled noradrenaline (NA); upon transmural electrical stimulation for 20 or 60 s (70 V, 1 ms, 3-35 Hz), the outflow of immunoreactive neuropeptide Y (ir-NPY) and NA was detected in the superfusion media. Ir-NPY was detected only following trains of 35 Hz for 60 s in both E and P. In contrast, tritium was released in a graded fashion following trains of 3, 15 or 35 Hz stimulation for 60 s in E, whereas in P it reached a plateau at frequencies larger than 15 Hz. The outflow of tritium, under present conditions, was dependent on the duration of the stimuli, while the release of ir-NPY was only evoked with stimuli of 60 s duration. In the absence of external Ca2+, neurotransmission was blocked and co-release of ir-NPY and NA was prevented.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Egtazic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Neuropeptide Y,
http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Tritium
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
14
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1300501-Animals,
pubmed-meshheading:1300501-Calcium,
pubmed-meshheading:1300501-Egtazic Acid,
pubmed-meshheading:1300501-Electric Stimulation,
pubmed-meshheading:1300501-Epididymis,
pubmed-meshheading:1300501-Kinetics,
pubmed-meshheading:1300501-Male,
pubmed-meshheading:1300501-Nerve Fibers,
pubmed-meshheading:1300501-Neuropeptide Y,
pubmed-meshheading:1300501-Norepinephrine,
pubmed-meshheading:1300501-Prostate,
pubmed-meshheading:1300501-Rats,
pubmed-meshheading:1300501-Rats, Sprague-Dawley,
pubmed-meshheading:1300501-Sympathetic Nervous System,
pubmed-meshheading:1300501-Time Factors,
pubmed-meshheading:1300501-Tritium,
pubmed-meshheading:1300501-Vas Deferens
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pubmed:year |
1992
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pubmed:articleTitle |
Co-release of neuropeptide Y (NPY) and noradrenaline from the sympathetic nerve terminals supplying the rat vas deferens; influence of calcium and the stimulation intensity.
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pubmed:affiliation |
Department of Physiology, Faculty of Biological Sciences, P. Catholic University of Chile, Santiago.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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