Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0030054,
umls-concept:C0030685,
umls-concept:C0034559,
umls-concept:C0037633,
umls-concept:C0242209,
umls-concept:C0391871,
umls-concept:C0599956,
umls-concept:C0680255,
umls-concept:C1280500,
umls-concept:C1283071,
umls-concept:C1382100,
umls-concept:C1704973,
umls-concept:C1963578
|
| pubmed:issue |
6
|
| pubmed:dateCreated |
1976-4-19
|
| pubmed:abstractText |
From gamma-irradiated oxygenated aqueous solutions of DNA, 2-deoxy-tetrodialdose (1) and 2-deoxy-pentos-4-ulose (2) have been isolated as free sugars. The formation of 1 indicates that in the presence of oxygen the DNA strand is not only broken by mere phosphate ester cleavage but also by C--C-bond rupture in the sugar moiety. Such a process has not been encountered in deoxygenated solutions so far. The mechanism for the formation of 1 is discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0341-0382
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
30
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
826-8
|
| pubmed:dateRevised |
2009-6-8
|
| pubmed:meshHeading | |
| pubmed:articleTitle |
Radiation chemistry of DNA, II. Strand breaks and sugar release by gamma-irradiation of DNA in aqueous solution. The effect of oxygen.
|
| pubmed:publicationType |
Journal Article
|