Linked Life Data

1299364

Source:http://linkedlifedata.com/resource/pubmed/id/1299364

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1993-5-20
pubmed:abstractText
Regional neural gene expression in Xenopus is the result of a number of processes that continue well beyond the end of gastrulation. By considering two of the basic features of neural induction, the duration of contact between mesoderm and ectoderm and the timing of neural competence, it has been possible to distinguish two phases in neural tissue formation. The late phase includes the period following gastrulation. A factor in determining regional neural gene expression is the difference in inducing ability of the mesoderm that develops during gastrulation along the anterior-posterior axis. The resulting ability to express regional neural genes is subsequently refined during the late phase by a signal that progresses from the posterior part of the embryo. Using a dorsal explant system, it is shown that this progressive signal can be mimicked by the addition of retinoic acid (RA). However, the observation that regions along the anterior-posterior axis respond in different ways to the addition of RA suggests that additional factors are also important in defining regional neural gene expression. One possibility is that the expression of retinoic acid receptors along the axis may demarcate regions that respond to RA in particular ways.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:author
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-7
pubmed:dateRevised
2010-8-25
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Retinoic acid and the late phase of neural induction.
pubmed:affiliation
Wellcome Trust and Cancer Research Campaign Institute of Cancer and Developmental Biology, Cambridge, UK.
pubmed:publicationType
Journal Article