Linked Life Data

1299129

Source:http://linkedlifedata.com/resource/pubmed/id/1299129

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1993-5-12
pubmed:abstractText
We have recently developed a model system for testing the necessity, appropriateness and sufficiency of individual components of the respiratory central pattern generator (CPG) in Lymnaea stagnalis. In order to examine the intrinsic and network properties of the three CPG interneurons (R.Pe.D1, V.D4 and Ip.3.I), these cells were isolated and cultured in vitro. All of these cells exhibited extensive neurite outgrowth within 18-24 h of plating in conditioned medium. These isolated neurons maintained their intrinsic properties in culture and also formed specific synapses with each other similar to those observed in vivo. However, only when all three interneurons were plated together was it possible to initiate the alternating rhythm characteristic of the respiratory activity observed in semi-intact or isolated brain preparations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0236-5383
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
409-19
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The respiratory central pattern generator (CPG) of Lymnaea reconstructed in vitro.
pubmed:affiliation
Department of Medical Physiology, University of Calgary, Alberta, Canada.
pubmed:publicationType
Journal Article