Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-9-16
pubmed:abstractText
The distribution and the appearance of foci of extracellular amorphous/granulofilamentous material (FEAM) in 34 human tumours are described. FEAM were rounded to oval, or more elongated or irregular elements of discretely delineated dense material lying in the extracellular space of tumours. They varied in size and abundance, sometimes coalescing into more extensive areas of dense material. At high magnification, FEAM exhibited a granular and finely filamentous substructure. Variations in the electron-density of FEAM were noted. Some FEAM were found associated with the surfaces of tumour cells, on occasion with subplasmalemmal linear densities. FEAM was also sometimes associated with matrix filaments, often collagen. Material of similar substructure and density was also associated with some vessels. FEAM were mostly found in tumours showing mesenchymal differentiation. The nature and origin of FEAM is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1122-9497
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-109
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Foci of amorphous/granulofilamentous matrix in the extracellular domain of tumours: a study of 34 cases. 1. Ultrastructural characterisation.
pubmed:affiliation
Department of Histopathology, Christie Hospital NHS Trust, Manchester, UK. brian.eyden@christie-tr.nwest.nhs.uk
pubmed:publicationType
Journal Article, Case Reports