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rdf:type |
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lifeskim:mentions |
umls-concept:C0021853,
umls-concept:C0022646,
umls-concept:C0023884,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0035820,
umls-concept:C0042105,
umls-concept:C0242738,
umls-concept:C0521447,
umls-concept:C0851285,
umls-concept:C1417825
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pubmed:issue |
4
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pubmed:dateCreated |
2003-9-15
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pubmed:abstractText |
Adaptive changes in transporter expression in liver and kidney provide alternative excretory pathways for biliary constituents during cholestasis and may thus attenuate liver injury. Whether adaptive changes in ATP-binding cassette (ABC) transporter expression are stimulated by bile acids and their nuclear receptor FXR is unknown.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Abcb11 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cholic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Multidrug Resistance-Associated...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Ursodeoxycholic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/farnesoid X-activated receptor,
http://linkedlifedata.com/resource/pubmed/chemical/multidrug resistance-associated...,
http://linkedlifedata.com/resource/pubmed/chemical/multidrug resistance-associated...
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:ArbeiterSilviaS,
pubmed-author:DenkHelmutH,
pubmed-author:FickertPeterP,
pubmed-author:FuchsbichlerAndreaA,
pubmed-author:GonzalezFrank JFJ,
pubmed-author:MarschallHanns-UlrichHU,
pubmed-author:SilbertDagmarD,
pubmed-author:TraunerMichaelM,
pubmed-author:WagnerMartinM,
pubmed-author:ZatloukalKurtK,
pubmed-author:ZollnerGernotG
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
480-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12971955-ATP-Binding Cassette Transporters,
pubmed-meshheading:12971955-Adaptation, Physiological,
pubmed-meshheading:12971955-Animals,
pubmed-meshheading:12971955-Cell Nucleus,
pubmed-meshheading:12971955-Cholic Acid,
pubmed-meshheading:12971955-DNA-Binding Proteins,
pubmed-meshheading:12971955-Intestines,
pubmed-meshheading:12971955-Kidney,
pubmed-meshheading:12971955-Liver,
pubmed-meshheading:12971955-Membrane Transport Proteins,
pubmed-meshheading:12971955-Mice,
pubmed-meshheading:12971955-Mice, Inbred C57BL,
pubmed-meshheading:12971955-Mice, Knockout,
pubmed-meshheading:12971955-Multidrug Resistance-Associated Proteins,
pubmed-meshheading:12971955-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:12971955-Transcription Factors,
pubmed-meshheading:12971955-Up-Regulation,
pubmed-meshheading:12971955-Ursodeoxycholic Acid
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pubmed:year |
2003
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pubmed:articleTitle |
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
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pubmed:affiliation |
Division of Gastroenterology and Hepatology, Department of Medicine, Karl-Franzens University, Auenbruggerplatz 15, A-8036 Graz, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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