|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0033684,
umls-concept:C0162807,
umls-concept:C0205341,
umls-concept:C0332285,
umls-concept:C0439148,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0887848,
umls-concept:C0936012,
umls-concept:C1333533,
umls-concept:C1334805,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C1704938,
umls-concept:C2348205
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1993-4-27
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
The predicted protein product of an anonymous clone isolated from a cDNA library prepared from 12 day post coitum (p.c) embryonic mouse heart tissue demonstrated the same segmental repeats previously identified in the cell division control protein, CDC4 and the G protein beta 1 subunit. A search of the protein database subsequently identified three other classes of protein containing the repeat. Secondary structure analyses performed on the repeat sequences revealed a high degree of conservation suggesting that the repeat motif performs a specific function in a diverse range of proteins.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1042-5179
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
3
|
|
pubmed:geneSymbol |
CDC4
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
213-20
|
|
pubmed:dateRevised |
2011-5-23
|
|
pubmed:meshHeading |
pubmed-meshheading:1296816-Amino Acid Sequence,
pubmed-meshheading:1296816-Animals,
pubmed-meshheading:1296816-Base Sequence,
pubmed-meshheading:1296816-Cell Cycle Proteins,
pubmed-meshheading:1296816-Cloning, Molecular,
pubmed-meshheading:1296816-DNA,
pubmed-meshheading:1296816-F-Box Proteins,
pubmed-meshheading:1296816-Fungal Proteins,
pubmed-meshheading:1296816-GTP-Binding Proteins,
pubmed-meshheading:1296816-Humans,
pubmed-meshheading:1296816-Mice,
pubmed-meshheading:1296816-Molecular Sequence Data,
pubmed-meshheading:1296816-Protein Structure, Secondary,
pubmed-meshheading:1296816-Proteins,
pubmed-meshheading:1296816-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:1296816-Sequence Alignment,
pubmed-meshheading:1296816-Sequence Homology, Amino Acid,
pubmed-meshheading:1296816-Ubiquitin-Protein Ligases
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
Secondary structure analysis identifies a putative mouse protein demonstrating similarity to the repeat units found in CDC4, the G protein beta subunits and related proteins.
|
|
pubmed:affiliation |
Department of Medicine, University of Cambridge, UK.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
