Linked Life Data

12963830

Source:http://linkedlifedata.com/resource/pubmed/id/12963830

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-9-9
pubmed:abstractText
Recently, we describe a biological role for endogenous CD45+ stem cells in maintaining muscle integrity by participating in regeneration. Our experiments further establish that Wnt-signaling is the mechanism by which resident CD45+ adult stem cells are induced to undergo myogenic specification during muscle regeneration. Importantly, our study suggests that targeting the Wnt-pathway represents a promising therapeutic approach for the treatment of neuromuscular degenerative diseases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1538-4101
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
418-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Adult stem cell specification by Wnt signaling in muscle regeneration.
pubmed:affiliation
Ottawa Health Research Institute, Molecular Medicine Program, Ottawa, Ontario, Canada.
pubmed:publicationType
Journal Article, Review