Source:http://linkedlifedata.com/resource/pubmed/id/12963761
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2003-9-9
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pubmed:abstractText |
The authors assessed the time of onset of the hypothermic effect of acetaminophen in 102 patients with acute ischemic stroke. These patients were randomized to treatment with either 1000 mg of acetaminophen (n = 52) or placebo (n = 50), given six times daily. Treatment with high-dose acetaminophen resulted in a 0.26 degrees C (95% CI 0.07 to 0.46 degrees C) lower mean body temperature than placebo treatment within 4 hours. This effect remained present throughout the next 20 hours. A large phase III trial seems warranted.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1526-632X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
9
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
677-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12963761-Acetaminophen,
pubmed-meshheading:12963761-Acute Disease,
pubmed-meshheading:12963761-Aged,
pubmed-meshheading:12963761-Body Temperature,
pubmed-meshheading:12963761-Brain Ischemia,
pubmed-meshheading:12963761-Double-Blind Method,
pubmed-meshheading:12963761-Female,
pubmed-meshheading:12963761-Humans,
pubmed-meshheading:12963761-Male,
pubmed-meshheading:12963761-Stroke,
pubmed-meshheading:12963761-Time Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Timing of the effect of acetaminophen on body temperature in patients with acute ischemic stroke.
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pubmed:affiliation |
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands. d.dippel@erasmusmc.nl
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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