Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2003-9-5
pubmed:abstractText
The aim of this study was to describe the epidemiology of gallbladder cancer in Scotland during the last 30 years. A secondary aim was to describe trends in cholecystectomy rates because it has been suggested that changing rates of cholecystectomy for benign gallbladder disease may be influencing the epidemiology of gallbladder cancer. A retrospective analysis of cancer registration and mortality (gallbladder cancer) and hospital discharge (cholecystectomy) data from Scotland in 1968-1998 was carried out. In Scotland the incidence of, and mortality from, gallbladder cancer have been falling in women since at least 1968, and in men since the late 1980s. Whilst overall survival remains poor, survival in older patients may have improved recently, and survival is better in patients from affluent areas. Cholecystectomy rates increased until 1977 then fell until the introduction of laparoscopic surgery caused them to return to the rates previously observed. The current declining incidence of gallbladder cancer in Scotland is probably, in part, related to the increasing cholecystectomy rates seen prior to 1977. Further studies addressing changes in stage at diagnosis and treatment provided are required to investigate the recent apparent improvement in survival of elderly gallbladder cancer patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0959-8049
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2080-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:12957463-Adolescent, pubmed-meshheading:12957463-Adult, pubmed-meshheading:12957463-Age Distribution, pubmed-meshheading:12957463-Age of Onset, pubmed-meshheading:12957463-Aged, pubmed-meshheading:12957463-Aged, 80 and over, pubmed-meshheading:12957463-Child, pubmed-meshheading:12957463-Child, Preschool, pubmed-meshheading:12957463-Cholecystectomy, pubmed-meshheading:12957463-Female, pubmed-meshheading:12957463-Gallbladder Neoplasms, pubmed-meshheading:12957463-Humans, pubmed-meshheading:12957463-Incidence, pubmed-meshheading:12957463-Infant, pubmed-meshheading:12957463-Infant, Newborn, pubmed-meshheading:12957463-Male, pubmed-meshheading:12957463-Middle Aged, pubmed-meshheading:12957463-Mortality, pubmed-meshheading:12957463-Retrospective Studies, pubmed-meshheading:12957463-Risk Factors, pubmed-meshheading:12957463-Scotland, pubmed-meshheading:12957463-Sex Distribution, pubmed-meshheading:12957463-Survival Analysis
pubmed:year
2003
pubmed:articleTitle
Epidemiology of gallbladder cancer and trends in cholecystectomy rates in Scotland, 1968-1998.
pubmed:affiliation
Information and Statistics Division of NHSScotland, Trinity Park House, South Trinity Road, Edinburgh EH5 3SQ, UK.
pubmed:publicationType
Journal Article