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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2003-9-5
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pubmed:abstractText |
Chromosome segregation and mitotic exit depend on activation of the anaphase-promoting complex (APC) by the substrate adaptor proteins CDC20 and CDH1. The APC is a ubiquitin ligase composed of at least 11 subunits. The interaction of APC2 and APC11 with E2 enzymes is sufficient for ubiquitination reactions, but the functions of most other subunits are unknown.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0960-9822
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1459-68
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12956947-Amino Acid Sequence,
pubmed-meshheading:12956947-Blotting, Western,
pubmed-meshheading:12956947-Cell Cycle,
pubmed-meshheading:12956947-Cell Cycle Proteins,
pubmed-meshheading:12956947-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:12956947-Humans,
pubmed-meshheading:12956947-Molecular Sequence Data,
pubmed-meshheading:12956947-Protein Conformation,
pubmed-meshheading:12956947-Sequence Homology,
pubmed-meshheading:12956947-Silver Staining,
pubmed-meshheading:12956947-Ubiquitin-Activating Enzymes,
pubmed-meshheading:12956947-Ubiquitin-Protein Ligase Complexes,
pubmed-meshheading:12956947-Ubiquitin-Protein Ligases
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pubmed:year |
2003
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pubmed:articleTitle |
TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1.
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pubmed:affiliation |
Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030, Vienna, Austria.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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