Linked Life Data

12952303

Source:http://linkedlifedata.com/resource/pubmed/id/12952303

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-9-3
pubmed:abstractText
Brain tumors were the first human malignancy to be targeted by therapeutic transfer of nucleic acids into somatic cells, a process also known as gene therapy. Malignant brain tumor cells in the adult brain have some unique biologic features, such as high mitotic activity on an essentially postmitotic background and virtually no tumor spread outside of the central nervous system. Brain tumors seem therefore to offer major advantages in the design of tumor-selective gene therapy strategies, and the role of gene therapy in malignant glioma has been investigated since the late 1980s, initially in numerous laboratory studies and later on in clinical trials.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1528-9117
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
180-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Gene therapy for human malignant brain tumors.
pubmed:affiliation
Department of Neurological Science, University of Liverpool, Liverpool L9 7LJ, UK. rainov@liv.ac.uk
pubmed:publicationType
Journal Article, Review