Linked Life Data

12951194

Source:http://linkedlifedata.com/resource/pubmed/id/12951194

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-9-2
pubmed:abstractText
We examined changes in the metencephalon of healthy adults who underwent magnetic resonance imaging twice, 5 years apart. The volumes of the cerebellar hemispheres, anterior and posterior vermis, declive-folium-tuber of the vermis, and the ventral pons were measured by operators unaware of subjects' characteristics and the time of scan. The cerebellar hemispheres and the cerebellar vermis, but not the ventral pons, were smaller in older people at both measurements. Significant linear shrinkage was observed in all examined metencephalic regions. Annualized rate of shrinkage was the greatest in the cerebellar hemispheres, somewhat smaller in the vermis, and minimal in the pons. Neither sex differences, nor sex-specific aging trends were found. We conclude that differential age-related shrinkage of the metencephalic structures occurs in healthy adults, but its magnitude differs from cross-sectional estimates.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
349
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Differential age-related changes in the regional metencephalic volumes in humans: a 5-year follow-up.
pubmed:affiliation
Institute of Gerontology, Wayne State University, Detroit, Detroit, MI 48202, USA. nraz@wayne.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.