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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-9-2
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pubmed:abstractText |
Hypertonicity of internal anal sphincter plays a major role in the persistence of chronic anal fissure. Botulinum toxin could induce internal anal sphincter relaxation without the adverse effects of surgery (long-term faecal incontinence) or topical nitrates (anal burning, headaches, hypotension).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0269-2813
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
515-24
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:12950424-Adolescent,
pubmed-meshheading:12950424-Adult,
pubmed-meshheading:12950424-Aged,
pubmed-meshheading:12950424-Botulinum Toxins,
pubmed-meshheading:12950424-Chronic Disease,
pubmed-meshheading:12950424-Double-Blind Method,
pubmed-meshheading:12950424-Female,
pubmed-meshheading:12950424-Fissure in Ano,
pubmed-meshheading:12950424-Humans,
pubmed-meshheading:12950424-Injections,
pubmed-meshheading:12950424-Male,
pubmed-meshheading:12950424-Middle Aged
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pubmed:year |
2003
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pubmed:articleTitle |
Lack of effficacy of botulinum toxin in chronic anal fissure.
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pubmed:affiliation |
Service des Maladies de l'Appareil Digestif, Hôpital de Pontchaillou, Rennes, France. laurent.siproudhis@chu-rennes.fr
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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