Source:http://linkedlifedata.com/resource/pubmed/id/12948685
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2003-9-1
|
| pubmed:abstractText |
General formulae are derived for the probability density and expected age of a mutation of frequency x in a population, and similarly for a mutation with b copies in a sample of n genes. A general formula is derived for the frequency spectrum of a mutation in a sample. Variable population size models are included. Results are derived in two frameworks: diffusion process models for the frequency of the mutation; and birth and death process models. The coalescent structure within the mutant gene group and the non-mutant group is considered.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0040-5809
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
64
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
241-51
|
| pubmed:meshHeading |
pubmed-meshheading:12948685-Alleles,
pubmed-meshheading:12948685-Birth Rate,
pubmed-meshheading:12948685-Gene Frequency,
pubmed-meshheading:12948685-Genetics, Population,
pubmed-meshheading:12948685-Mathematics,
pubmed-meshheading:12948685-Models, Genetic,
pubmed-meshheading:12948685-Mortality,
pubmed-meshheading:12948685-Mutation,
pubmed-meshheading:12948685-Population Density,
pubmed-meshheading:12948685-Probability,
pubmed-meshheading:12948685-Reproduction
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
The frequency spectrum of a mutation, and its age, in a general diffusion model.
|
| pubmed:affiliation |
Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK. griff@stats.ox.ac.uk
|
| pubmed:publicationType |
Journal Article
|