12948010

Source:http://linkedlifedata.com/resource/pubmed/id/12948010

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005528, umls-concept:C0013227, umls-concept:C0178499, umls-concept:C0687133, umls-concept:C0872351, umls-concept:C1527178, umls-concept:C1706937
pubmed:issue	8
pubmed:dateCreated	2003-9-1
pubmed:abstractText	The purpose of this study was to investigate the pH-dependent passive and active transport of weakly basic drugs across the human intestinal epithelium.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8406521
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Digoxin, http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein, http://linkedlifedata.com/resource/pubmed/chemical/Pharmaceutical Preparations
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0724-8741
pubmed:author	pubmed-author:ArturssonPerP, pubmed-author:NeuhoffSibylleS, pubmed-author:UngellAnna-LenaAL, pubmed-author:ZamoraIsmaelI
pubmed:issnType	Print
pubmed:volume	20
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1141-8
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:12948010-Biological Transport, pubmed-meshheading:12948010-Caco-2 Cells, pubmed-meshheading:12948010-Cell Membrane Permeability, pubmed-meshheading:12948010-Digoxin, pubmed-meshheading:12948010-Drug Interactions, pubmed-meshheading:12948010-Humans, pubmed-meshheading:12948010-Hydrogen-Ion Concentration, pubmed-meshheading:12948010-Intestinal Mucosa, pubmed-meshheading:12948010-P-Glycoprotein, pubmed-meshheading:12948010-Pharmaceutical Preparations, pubmed-meshheading:12948010-Pharmacokinetics
pubmed:year	2003
pubmed:articleTitle	pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions.
pubmed:affiliation	AstraZeneca, DMPK & Bioanalytical Chemistry, SE-431 83 Mölndal, Sweden.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't