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12947321
Source:
http://linkedlifedata.com/resource/pubmed/id/12947321
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0021467
,
umls-concept:C0021469
,
umls-concept:C0033681
,
umls-concept:C0346647
,
umls-concept:C0920779
pubmed:issue
2
pubmed:dateCreated
2003-8-29
pubmed:abstractText
Src is a 60-kDa tyrosine kinase that plays a critical role in signal transduction associated with cell-extracellular matrix interactions. We tested the hypothesis that Src inhibition might suppress pancreatic cancer cellular invasiveness.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/0417347
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 2
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9
,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins pp60(c-src)
,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles
,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines
,
http://linkedlifedata.com/resource/pubmed/chemical/pyrazolopyridine
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0039-6060
pubmed:author
pubmed-author:AshleyStanley WSW
,
pubmed-author:Gardner-ThorpeJamesJ
,
pubmed-author:ItoHiromichiH
,
pubmed-author:WhangEdward EEE
,
pubmed-author:ZinnerMichael JMJ
pubmed:issnType
Print
pubmed:volume
134
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-6
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:12947321-Cell Division
,
pubmed-meshheading:12947321-Enzyme Inhibitors
,
pubmed-meshheading:12947321-Humans
,
pubmed-meshheading:12947321-Matrix Metalloproteinase 2
,
pubmed-meshheading:12947321-Matrix Metalloproteinase 9
,
pubmed-meshheading:12947321-Neoplasm Invasiveness
,
pubmed-meshheading:12947321-Pancreatic Neoplasms
,
pubmed-meshheading:12947321-Phosphorylation
,
pubmed-meshheading:12947321-Proto-Oncogene Proteins pp60(c-src)
,
pubmed-meshheading:12947321-Pyrazoles
,
pubmed-meshheading:12947321-Pyridines
,
pubmed-meshheading:12947321-Tumor Cells, Cultured
pubmed:year
2003
pubmed:articleTitle
Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness.
pubmed:affiliation
Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
pubmed:publicationType
Journal Article
,
Research Support, Non-U.S. Gov't