rdf:type |
|
lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0018131,
umls-concept:C0022131,
umls-concept:C0023688,
umls-concept:C0205245,
umls-concept:C0314603,
umls-concept:C0332206,
umls-concept:C0333386,
umls-concept:C0450127,
umls-concept:C0524914,
umls-concept:C1308752,
umls-concept:C1332822,
umls-concept:C1367714,
umls-concept:C1442161,
umls-concept:C1706327,
umls-concept:C1709854
|
pubmed:issue |
2
|
pubmed:dateCreated |
2003-8-29
|
pubmed:abstractText |
Interaction of chemokine receptor CXCR3 with its ligand IP-10 mediates effector cell trafficking to sites of allograft rejection in murine models of whole organ allotransplantation. We hypothesized that blocking the CXCR3/IP-10 interaction would impair posttransplantation leukocyte trafficking to and delay rejection of pancreatic islet allografts.
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pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL10,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CXC,
http://linkedlifedata.com/resource/pubmed/chemical/Cxcr3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR3,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0039-6060
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
134
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
126-33
|
pubmed:dateRevised |
2011-8-24
|
pubmed:meshHeading |
pubmed-meshheading:12947308-Animals,
pubmed-meshheading:12947308-Antibodies,
pubmed-meshheading:12947308-Chemokine CXCL10,
pubmed-meshheading:12947308-Chemokines,
pubmed-meshheading:12947308-Chemokines, CXC,
pubmed-meshheading:12947308-Diabetes Mellitus, Experimental,
pubmed-meshheading:12947308-Gene Deletion,
pubmed-meshheading:12947308-Graft Survival,
pubmed-meshheading:12947308-Islets of Langerhans,
pubmed-meshheading:12947308-Islets of Langerhans Transplantation,
pubmed-meshheading:12947308-Ligands,
pubmed-meshheading:12947308-Lymphocytes,
pubmed-meshheading:12947308-Male,
pubmed-meshheading:12947308-Mice,
pubmed-meshheading:12947308-Mice, Inbred C57BL,
pubmed-meshheading:12947308-Mice, Inbred Strains,
pubmed-meshheading:12947308-Receptors, CXCR3,
pubmed-meshheading:12947308-Receptors, Chemokine,
pubmed-meshheading:12947308-Transplantation, Homologous
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pubmed:year |
2003
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pubmed:articleTitle |
Genetic deletion of chemokine receptor CXCR3 or antibody blockade of its ligand IP-10 modulates posttransplantation graft-site lymphocytic infiltrates and prolongs functional graft survival in pancreatic islet allograft recipients.
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pubmed:affiliation |
Departments of Surgery and Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|