|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
1993-4-13
|
|
pubmed:abstractText |
A series of novel 2-pyridyl-2-thiobenzothiazole compounds was prepared and investigated by a number of in vitro methods in order to determine their anti-inflammatory properties. Results are discussed with reference to well known NSAIDs. (3-carboxy-2-pyridyl)-2-thiobenzothiazole had the most potent anti-inflammatory activity, being 1.34 times more active than indomethacin used as reference compound.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0014-827X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
47
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1477-85
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1294164-Animals,
pubmed-meshheading:1294164-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:1294164-Carrageenan,
pubmed-meshheading:1294164-Cattle,
pubmed-meshheading:1294164-Dinoprostone,
pubmed-meshheading:1294164-Edema,
pubmed-meshheading:1294164-Free Radicals,
pubmed-meshheading:1294164-Humans,
pubmed-meshheading:1294164-Indomethacin,
pubmed-meshheading:1294164-Male,
pubmed-meshheading:1294164-Rats,
pubmed-meshheading:1294164-Rats, Wistar,
pubmed-meshheading:1294164-Synovial Fluid,
pubmed-meshheading:1294164-Thiazoles
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
Synthesis and anti-inflammatory activity of 2-pyridyl-2-thiobenzothiazole derivatives.
|
|
pubmed:affiliation |
Department of Therapeutic and Organic Chemistry, Faculty of Pharmacy, University of Limoges, France.
|
|
pubmed:publicationType |
Journal Article,
In Vitro
|
