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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-8-25
pubmed:abstractText
The aim of the present study was to investigate the differences in postmortem blood biochemistry between fresh-, saltwater drowning and acute myocardial infarction/ischemia (AMI) (n=11, n=15 and n=23, respectively; postmortem interval <48 h). Left and right cardiac blood samples were examined for the serum markers: sodium (Na), chloride (Cl), magnesium (Mg), blood urea nitrogen (BUN), creatinine (Cr), pulmonary surfactant-associated protein A (SP-A) and cardiac troponin T (cTn-T). The most efficient markers were the left-right cardiac BUN ratio for determination of drowning (hemodilution) and the left heart blood Mg level for differentiation between fresh- and saltwater aspiration. A characteristic feature of saltwater drowning was a low left-right BUN ratio and a marked elevation in the serum Cl, Mg and Ca levels of the left heart blood. Serum cTn-T level was usually low in drownings, showing a difference from most cases of AMI. Freshwater drowning showed a significant elevation of serum SP-A, although there was considerable overlapping with saltwater drowning and AMI. These findings suggested the usefulness of serum markers in the investigation of death from drownings.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1344-6223
pubmed:author
pubmed:issnType
Print
pubmed:volume
5 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S298-301
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12935616-Acute Disease, pubmed-meshheading:12935616-Adolescent, pubmed-meshheading:12935616-Adult, pubmed-meshheading:12935616-Aged, pubmed-meshheading:12935616-Aged, 80 and over, pubmed-meshheading:12935616-Biological Markers, pubmed-meshheading:12935616-Blood Urea Nitrogen, pubmed-meshheading:12935616-Calcium, pubmed-meshheading:12935616-Child, pubmed-meshheading:12935616-Child, Preschool, pubmed-meshheading:12935616-Chlorides, pubmed-meshheading:12935616-Diagnosis, Differential, pubmed-meshheading:12935616-Drowning, pubmed-meshheading:12935616-Female, pubmed-meshheading:12935616-Fresh Water, pubmed-meshheading:12935616-Humans, pubmed-meshheading:12935616-Infant, pubmed-meshheading:12935616-Infant, Newborn, pubmed-meshheading:12935616-Magnesium, pubmed-meshheading:12935616-Male, pubmed-meshheading:12935616-Middle Aged, pubmed-meshheading:12935616-Myocardial Infarction, pubmed-meshheading:12935616-Pulmonary Surfactant-Associated Protein A, pubmed-meshheading:12935616-Seawater, pubmed-meshheading:12935616-Troponin T
pubmed:year
2003
pubmed:articleTitle
Possible postmortem serum markers for differentiation between fresh-, saltwater drowning and acute cardiac death: a preliminary investigation.
pubmed:affiliation
Department of Legal Medicine, Osaka City University Medical School, Asahi-machi 1-4-3, Abeno, Osaka 545-8585, Japan. baolizhu@med.osaka-cu.ac.jp
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't