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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1993-4-1
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pubmed:abstractText |
Flow cytometric DNA analysis was performed on 19 adrenal pheochromocytomas and 6 extra-adrenal paragangliomas in parallel with clinical and histopathological review to determine the usefulness of this technique to predict biologic behavior of these tumors. In pheochromocytomas and paragangliomas, tetraploidy or near-tetraploidy occurred in 32% and 33% and aneuploidy in 10% and none respectively. A case of malignant pheochromocytoma had diploid DNA content. Occurrence of aneuploidy or tetraploidy is frequent in clinically benign tumors in conjunction with a marked degree of nuclear atypia and cannot be a predictor of malignancy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0513-5796
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
249-57
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1292249-Adolescent,
pubmed-meshheading:1292249-Adrenal Gland Neoplasms,
pubmed-meshheading:1292249-Adult,
pubmed-meshheading:1292249-Age Factors,
pubmed-meshheading:1292249-Child,
pubmed-meshheading:1292249-DNA, Neoplasm,
pubmed-meshheading:1292249-Female,
pubmed-meshheading:1292249-Flow Cytometry,
pubmed-meshheading:1292249-Humans,
pubmed-meshheading:1292249-Male,
pubmed-meshheading:1292249-Middle Aged,
pubmed-meshheading:1292249-Mitosis,
pubmed-meshheading:1292249-Paraganglioma,
pubmed-meshheading:1292249-Pheochromocytoma,
pubmed-meshheading:1292249-Ploidies
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pubmed:year |
1992
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pubmed:articleTitle |
DNA flow cytometry in pheochromocytoma and paraganglioma.
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pubmed:affiliation |
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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