| pubmed-article:12922143 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0318711 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0039005 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0013878 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0085408 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0332161 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0003261 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0018014 | lld:lifeskim |
| pubmed-article:12922143 | lifeskim:mentions | umls-concept:C0332283 | lld:lifeskim |
| pubmed-article:12922143 | pubmed:issue | 25-26 | lld:pubmed |
| pubmed-article:12922143 | pubmed:dateCreated | 2003-8-18 | lld:pubmed |
| pubmed-article:12922143 | pubmed:abstractText | We evaluated antibody responses and protection induced by attenuated Wa human rotavirus (AttHRV) and VP2/6-rotavirus-like particles (VLP), 100 or 250 microg/dose, with immunostimulating complexes (ISCOM) (VLP/ISCOM) each given orally, alone or sequentially to gnotobiotic pigs. The AttHRV-VLP 250 microg/ISCOM and three-dose-AttHRV (AttHRV3x) groups had significantly higher serum IgA, IgG and intestinal IgA antibody titers to HRV pre-challenge than the three-dose-VLP 100 microg/ISCOM group (VLP/ISCOM3x) and controls (diluent/ISCOMmatrix). Protection rates against viral shedding and diarrhea were highest in the AttHRV-VLP250 microg/ISCOM and AttHRV3x groups, lower in the AttHRV-VLP 100 microg/ISCOM group, with no protection in the VLP/ISCOM3x group and controls. Thus, VLP/ISCOM boosted antibody titers and protection after priming with AttHRV. | lld:pubmed |
| pubmed-article:12922143 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12922143 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12922143 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12922143 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:12922143 | pubmed:issn | 0264-410X | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:LewisPP | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:NielsenPP | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:KimYY | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:MoreinBB | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:YuanLL | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:SaifL JLJ | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:NguyenT VTV | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:JeongKK | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:IosefCC | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:Lovgren-Bengt... | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:ChangK-OKO | lld:pubmed |
| pubmed-article:12922143 | pubmed:author | pubmed-author:AzevedoM S... | lld:pubmed |
| pubmed-article:12922143 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12922143 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:12922143 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:12922143 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12922143 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12922143 | pubmed:pagination | 4059-70 | lld:pubmed |
| pubmed-article:12922143 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
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| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:meshHeading | pubmed-meshheading:12922143... | lld:pubmed |
| pubmed-article:12922143 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12922143 | pubmed:articleTitle | Protection and antibody responses to oral priming by attenuated human rotavirus followed by oral boosting with 2/6-rotavirus-like particles with immunostimulating complexes in gnotobiotic pigs. | lld:pubmed |
| pubmed-article:12922143 | pubmed:affiliation | Food Animal Health Research Program, Department of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691-4096, USA. | lld:pubmed |
| pubmed-article:12922143 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12922143 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12922143 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12922143 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12922143 | lld:pubmed |
