Linked Life Data

12919079

Source:http://linkedlifedata.com/resource/pubmed/id/12919079

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-8-15
pubmed:abstractText
Neurotrophin 3 (NT3), a member of the neurotrophin family, and its specific receptor tyrosine kinase C (TrkC) are involved in the differentiation, survival, and maintenance of many neuronal populations. Recently, NT3 and TrkC were also retained involved in the biology of non-neuronal tissues. In this study, we report the presence of NT3- and TrkC-immunoreactive cells in the endocrine pancreas of adult buffalos. They were usually distributed at the periphery of islets and showed intense immunoreactivity. By double immunohistochemical staining, NT3- and TrkC-IR resulted to be colocalized in glucagon immunoreactive cells. These findings suggest endocrine and/or autocrine roles of NT3 in pancreatic A cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0340-2096
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-6
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Neurotrophin 3 and its receptor TrkC immunoreactivity in glucagon cells of buffalo pancreas.
pubmed:affiliation
Dip Strutture, funzioni e tecnologie biologiche, Università di Napoli "Federico II", Italy. lucini@unina.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't