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rdf:type |
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lifeskim:mentions |
umls-concept:C0001175,
umls-concept:C0012854,
umls-concept:C0024398,
umls-concept:C0026336,
umls-concept:C0036638,
umls-concept:C0085432,
umls-concept:C0086022,
umls-concept:C0205171,
umls-concept:C0332283,
umls-concept:C0442335,
umls-concept:C0449435,
umls-concept:C0857515,
umls-concept:C1705099
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pubmed:issue |
17
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pubmed:dateCreated |
2003-8-13
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pubmed:abstractText |
We previously demonstrated the excellent protective efficacy of DNA priming followed by Gag-expressing Sendai virus (SeV) boosting (DNA prime/SeV-Gag boost vaccine) against a pathogenic simian-human immunodeficiency virus (SHIV89.6PD) infection in macaques. Here we show that we established a practical, safer AIDS vaccine protocol, a single DNA priming followed by a single booster with a recently developed replication-defective F deletion SeV-expressing Gag, and show its protective efficacy against SHIV89.6PD infections.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10075982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10386336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10448136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10864670,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10869776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10894297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-10899028,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-11039923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-11393868,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-11551502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-11689672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-11797011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-12029153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-1331148,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-6296831,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-8057491,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-8207839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9034340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9078386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9160521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9237701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9294140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9420212,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9516110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9732063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12915583-9933172
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
77
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9710-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12915583-AIDS Vaccines,
pubmed-meshheading:12915583-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:12915583-Animals,
pubmed-meshheading:12915583-CD4-Positive T-Lymphocytes,
pubmed-meshheading:12915583-CD8-Positive T-Lymphocytes,
pubmed-meshheading:12915583-DNA, Viral,
pubmed-meshheading:12915583-Defective Viruses,
pubmed-meshheading:12915583-Disease Models, Animal,
pubmed-meshheading:12915583-Genes, gag,
pubmed-meshheading:12915583-Genetic Vectors,
pubmed-meshheading:12915583-Humans,
pubmed-meshheading:12915583-Immunization, Secondary,
pubmed-meshheading:12915583-Macaca fascicularis,
pubmed-meshheading:12915583-Macaca mulatta,
pubmed-meshheading:12915583-SAIDS Vaccines,
pubmed-meshheading:12915583-Sendai virus,
pubmed-meshheading:12915583-Simian Acquired Immunodeficiency Syndrome,
pubmed-meshheading:12915583-Vaccines, DNA
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pubmed:year |
2003
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pubmed:articleTitle |
Protective efficacy of an AIDS vaccine, a single DNA priming followed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model.
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pubmed:affiliation |
Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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