Linked Life Data

12913302

Source:http://linkedlifedata.com/resource/pubmed/id/12913302

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2003-8-12
pubmed:abstractText
Known polyene amide, clathrynamide A, and three novel related metabolites, debromoclathrynamide A, (4E,6E)-debromoclathrynamide A and (6E)-clathrynamide A, were isolated from an Okinawan marine sponge, Psammoclemma sp. The absolute stereochemistry of clathrynamide A was determined to be 3R,12R by the modified Mosher method. The structures of the three new compounds were elucidated by spectroscopic analyses as debromo derivatives and geometrical isomers. Their antifungal activities were also evaluated with a phytopathogenic fungus, indicating that both the bromine atom and double-bond geometry affected the activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0916-8451
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1568-73
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Structural studies and antifungal activity of unique polyene amides, clathrynamide A and three new derivatives, from a marine sponge, Psammoclemma sp.
pubmed:affiliation
Graduate School of Bioagricultural Sciences, Nagoya University, Japan. ojika@agr.nagoya-u.ac.jp
pubmed:publicationType
Journal Article