Source:http://linkedlifedata.com/resource/pubmed/id/12913098
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19
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pubmed:dateCreated |
2003-9-26
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pubmed:abstractText |
A significant number of patients who develop recurrence after a histopathologically negative sentinel lymph node (SLN) biopsy will demonstrate occult metastases on re-evaluation of the SLNs with serial sectioning and immunohistochemistry. Reverse transcriptase polymerase chain reaction (RT-PCR) has been evaluated to improve disease staging and avoid false-negative findings in fresh or frozen-section SLNs. The purpose of this study was to develop a multimarker RT-PCR assay for assessing melanoma patients' archived paraffin-embedded (PE) SLNs.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0732-183X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3566-72
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12913098-Adult,
pubmed-meshheading:12913098-Female,
pubmed-meshheading:12913098-Genetic Markers,
pubmed-meshheading:12913098-Humans,
pubmed-meshheading:12913098-Male,
pubmed-meshheading:12913098-Melanoma,
pubmed-meshheading:12913098-Middle Aged,
pubmed-meshheading:12913098-Neoplasm Metastasis,
pubmed-meshheading:12913098-Predictive Value of Tests,
pubmed-meshheading:12913098-Prognosis,
pubmed-meshheading:12913098-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12913098-Sentinel Lymph Node Biopsy,
pubmed-meshheading:12913098-Skin Neoplasms,
pubmed-meshheading:12913098-Specimen Handling,
pubmed-meshheading:12913098-Treatment Outcome
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pubmed:year |
2003
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pubmed:articleTitle |
Prediction of disease outcome in melanoma patients by molecular analysis of paraffin-embedded sentinel lymph nodes.
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pubmed:affiliation |
Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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