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pubmed-article:12911786pubmed:abstractTextIL-4 by binding to its receptor (IL-4R) is essential for the development of airway inflammation present in asthma, through the induction of IgE synthesis in B cells and differentiation of T cells to a Th2 phenotype.lld:pubmed
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pubmed-article:12911786pubmed:articleTitlePolymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.lld:pubmed
pubmed-article:12911786pubmed:affiliationDivisions of Human Genetics Infection, Inflammation and Repair, School of Medicine, University of Southampton, UK. bianca.beghe@unipd.itlld:pubmed
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