|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2003-8-12
|
|
pubmed:abstractText |
IL-4 by binding to its receptor (IL-4R) is essential for the development of airway inflammation present in asthma, through the induction of IgE synthesis in B cells and differentiation of T cells to a Th2 phenotype.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0954-7894
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
33
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1111-7
|
|
pubmed:dateRevised |
2010-3-23
|
|
pubmed:meshHeading |
pubmed-meshheading:12911786-Adolescent,
pubmed-meshheading:12911786-Adult,
pubmed-meshheading:12911786-Asthma,
pubmed-meshheading:12911786-Case-Control Studies,
pubmed-meshheading:12911786-Child,
pubmed-meshheading:12911786-Child, Preschool,
pubmed-meshheading:12911786-Female,
pubmed-meshheading:12911786-Gene Frequency,
pubmed-meshheading:12911786-Genetic Predisposition to Disease,
pubmed-meshheading:12911786-Genotype,
pubmed-meshheading:12911786-Haplotypes,
pubmed-meshheading:12911786-Humans,
pubmed-meshheading:12911786-Hypersensitivity, Immediate,
pubmed-meshheading:12911786-Interleukin-4,
pubmed-meshheading:12911786-Linkage Disequilibrium,
pubmed-meshheading:12911786-Male,
pubmed-meshheading:12911786-Phenotype,
pubmed-meshheading:12911786-Polymorphism, Genetic,
pubmed-meshheading:12911786-Receptors, Interleukin-4,
pubmed-meshheading:12911786-Statistics as Topic
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.
|
|
pubmed:affiliation |
Divisions of Human Genetics Infection, Inflammation and Repair, School of Medicine, University of Southampton, UK. bianca.beghe@unipd.it
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
