rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11
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pubmed:dateCreated |
1993-4-1
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pubmed:abstractText |
The system Fe(2+)-ascorbate was used for lipid peroxidation (LPO) activation in isolated heart tissue. The stimulation of free radical processes in the myocardium caused a rise in the level of LPO products and a significant lowering of that of prostacyclin. Intravenous injection of synthetic analogues of enkephalins before LPO activation inhibited LPO and resulted in prostacyclin synthesis normalization. The addition of peptides under study into perfusion solution led to a decrease in LPO primary products level and in thromboxane synthesis.
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pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Enkephalin, Leucine-2-Alanine,
http://linkedlifedata.com/resource/pubmed/chemical/Enkephalin, Methionine,
http://linkedlifedata.com/resource/pubmed/chemical/Enkephalins,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radicals,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandins,
http://linkedlifedata.com/resource/pubmed/chemical/Thromboxanes,
http://linkedlifedata.com/resource/pubmed/chemical/enkephalin, Met(2)-ProNH2(5)-,
http://linkedlifedata.com/resource/pubmed/chemical/enkephalin-Leu, Ala(2)-Arg(6)-
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0365-9615
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
114
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
468-70
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:1290811-Animals,
pubmed-meshheading:1290811-Enkephalin, Leucine-2-Alanine,
pubmed-meshheading:1290811-Enkephalin, Methionine,
pubmed-meshheading:1290811-Enkephalins,
pubmed-meshheading:1290811-Female,
pubmed-meshheading:1290811-Free Radicals,
pubmed-meshheading:1290811-Heart,
pubmed-meshheading:1290811-Lipid Peroxidation,
pubmed-meshheading:1290811-Myocardium,
pubmed-meshheading:1290811-Prostaglandins,
pubmed-meshheading:1290811-Rats,
pubmed-meshheading:1290811-Thromboxanes
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pubmed:year |
1992
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pubmed:articleTitle |
[The effect of synthetic enkephalins on prostaglandin synthesis and lipid peroxidation in the isolated heart during the activation of free-radical processes].
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
English Abstract
|