|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011306,
umls-concept:C0017262,
umls-concept:C0027540,
umls-concept:C0027950,
umls-concept:C0039194,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0243144,
umls-concept:C0264939,
umls-concept:C0392756,
umls-concept:C0871261,
umls-concept:C1366561,
umls-concept:C1413243,
umls-concept:C1515895,
umls-concept:C1516044,
umls-concept:C1539081,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2347946,
umls-concept:C2911684,
umls-concept:C2911692
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2003-8-7
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|
pubmed:abstractText |
There is a breakdown of tolerance to neutrophil components during systemic vasculitis, which is marked by autoantibodies and T cells with specificity for proteinase 3 or myeloperoxidase, expressed on the surface of apoptotic neutrophils. This study was undertaken to investigate the effects of human apoptotic and necrotic neutrophils on human dendritic cell (DC) phenotype and ability to stimulate allogeneic T cell proliferation.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD40,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD86,
http://linkedlifedata.com/resource/pubmed/chemical/CD86 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins
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pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
48
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2362-74
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12905492-Antigens, CD,
pubmed-meshheading:12905492-Antigens, CD40,
pubmed-meshheading:12905492-Antigens, CD80,
pubmed-meshheading:12905492-Antigens, CD86,
pubmed-meshheading:12905492-Apoptosis,
pubmed-meshheading:12905492-Cell Division,
pubmed-meshheading:12905492-Dendritic Cells,
pubmed-meshheading:12905492-Down-Regulation,
pubmed-meshheading:12905492-Humans,
pubmed-meshheading:12905492-Immunophenotyping,
pubmed-meshheading:12905492-Membrane Glycoproteins,
pubmed-meshheading:12905492-Necrosis,
pubmed-meshheading:12905492-Neutrophils,
pubmed-meshheading:12905492-Phagocytosis,
pubmed-meshheading:12905492-T-Lymphocytes,
pubmed-meshheading:12905492-Up-Regulation
|
|
pubmed:year |
2003
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|
pubmed:articleTitle |
Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: relevance to systemic vasculitis.
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|
pubmed:affiliation |
MRC Centre for Immune Regulation, University of Birmingham Medical School, Birmingham B15 2TT, UK.
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pubmed:publicationType |
Journal Article,
In Vitro
|
