Source:http://linkedlifedata.com/resource/pubmed/id/12904199
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2003-8-7
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pubmed:abstractText |
Intoxication with 280 mg of amlodipine caused severe hypotension, third-degree heart block and hyperkalaemia in a 36-year-old female patient. The patient was initially treated with fluids, dopamine, calcium chloride, and epinephrine without effect. The patient was then given a bolus injection of insulin and glucose as a temporary mean to treat the hyperkalaemia. We observed a rise in blood pressure (BP) after insulin was given and the BP was subsequently responsive to epinephrine. A possible positive inotropic effect of insulin therapy in patients with calcium channel blocker intoxication is in accordance with previous findings. In conclusion, it is suggested that hyperinsulinaemia-euglycaemia therapy may be considered as a first-line therapy in calcium channel blocker intoxication.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0001-5172
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1038-40
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading | |
pubmed:year |
2003
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pubmed:articleTitle |
Severe intoxication after an intentional overdose of amlodipine.
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pubmed:affiliation |
Department of Anaesthesiology Silkeborg County Hospital, Epidemiology and Social Medicine, University of Aarhus, Denmark.
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pubmed:publicationType |
Journal Article,
Case Reports
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