|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003402,
umls-concept:C0023779,
umls-concept:C0032105,
umls-concept:C0596620,
umls-concept:C0681850,
umls-concept:C1280433,
umls-concept:C1280500,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2003-8-6
|
|
pubmed:abstractText |
Ten HIV-infected nucleoside reverse transcriptase inhibitor-treated subjects with lipoatrophy or sustained hyperlactatemia were given antioxidants: vitamins C, E, and N-acetyl cysteine. After 24 weeks, anthropometrics did not change significantly, except for a modest decrease in the waist-to-hip ratio. Fasting low-density lipoprotein cholesterol trended toward lower values. Fasting glucose significantly increased along with a significant increase in homeostatic model assessment values, reflecting an increase in insulin resistance. Controlled trials are required to evaluate directly the effects of these agents on lipid and glucose metabolism.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1525-4135
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
33
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
605-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12902805-Acetylcysteine,
pubmed-meshheading:12902805-Adult,
pubmed-meshheading:12902805-Antioxidants,
pubmed-meshheading:12902805-Ascorbic Acid,
pubmed-meshheading:12902805-Body Composition,
pubmed-meshheading:12902805-Cholesterol,
pubmed-meshheading:12902805-Female,
pubmed-meshheading:12902805-Glucose,
pubmed-meshheading:12902805-HIV-Associated Lipodystrophy Syndrome,
pubmed-meshheading:12902805-Hospitals, University,
pubmed-meshheading:12902805-Humans,
pubmed-meshheading:12902805-Lipids,
pubmed-meshheading:12902805-Male,
pubmed-meshheading:12902805-Middle Aged,
pubmed-meshheading:12902805-Ohio,
pubmed-meshheading:12902805-Pilot Projects,
pubmed-meshheading:12902805-Reverse Transcriptase Inhibitors,
pubmed-meshheading:12902805-Vitamin E
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|
pubmed:year |
2003
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|
pubmed:articleTitle |
Effect of antioxidants on glucose metabolism and plasma lipids in HIV-infected subjects with lipoatrophy.
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|
pubmed:affiliation |
Rainbow Babies and Children's Hospital, Cleveland, Ohio 44106, USA. mccomsey.grace@clevelandactu.org
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
